Friday, July 26, 2013

This Video Montage of Saturn s Rings and Moons Is Simply Gorgeous

For more than nine years, NASA?s Cassini probe has orbited Saturn, examining its rings and moons in unprecedented detail and sending back images of things and places humans had never seen. Filmmaker Fabio di Donato has managed to collapse that discovery and wonder into four minutes. In a new film posted on Vimeo, di Donato cobbled together countless still images of the Saturnian system to compose a beautiful, literally otherworldly montage.

Among the stars of the film: Saturn?s tiny moonlets, which subtly warp the giant planet?s rings; the pockmarked moon Mimas, which bears an uncanny resemblance to the Star Wars Death Star; and the two-toned satellite Iapetus, which has one bright hemisphere and one dark one.

The film?s source material is publicly available?Cassini is a taxpayer-funded mission, and its images are distributed freely. The mission, which has captivated scientists and citizens alike, is planetary exploration at its best?a perfect example of why NASA must protect its imperiled planetary science programs, as we argued in an editorial last year.

Source: http://rss.sciam.com/~r/sciam/basic-science/~3/ks_ZxSlTkY4/post.cfm

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Thursday, July 25, 2013

Sony Gets 'Gran Turismo' Video Game for 'Social Network' Producers

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Source: http://www.facebook.com/firstshowing/posts/10151501490681400

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Amanda Bynes to run for Memphis Mayor?

Amanda Bynes to run for Memphis Mayor?

Posted by Danny Bader on Wed, Jul 24, 2013 at 1:59 PM

Memphis? Is child star/outsider weapons designer Amanda Bynes considering a run for the Memphis Mayor's office?

When asked to comment on a possible Bynes platform, an area politico who asked not to be named suggested that she might surround Mud Island with sharks and turn it into a prison for drug offenders.

"She said she'd get rid of all the rats," our source claims.

"Then she screamed at me and threw gas on what looked like a dog."

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Obama: Washington has 'taken eye off' the economy

President Barack Obama speaks about the economy, Wednesday, July 24, 2013, at Knox College in Galesburg, Ill. Seeking to focus public attention on the problem he was sent to the White House to solve, Obama is making a renewed push for policies to expand the middle class, helping people he says are still treading water years after the financial meltdown. (AP Photo/Susan Walsh)

President Barack Obama speaks about the economy, Wednesday, July 24, 2013, at Knox College in Galesburg, Ill. Seeking to focus public attention on the problem he was sent to the White House to solve, Obama is making a renewed push for policies to expand the middle class, helping people he says are still treading water years after the financial meltdown. (AP Photo/Susan Walsh)

President Barack Obama gestures as he talks about his vision for rebuilding the economy, Wednesday, July 24, 2013, at Knox College in Galesburg Ill. The president repackaged his economic message, a six-point plan for putting a floor under the country's diminishing middle class, and lashed out at opponents for creating "an endless parade of distractions, political posturing and phony scandals." (AP Photo/Seth Perlman)

President Barack Obama speaks at the University of Central Missouri in Warrensburg, Mo., Wednesday, July 24, 2013. Obama hit the road to deliver remarks in Illinois and Missouri kicking off a series of speeches that lay out his vision for rebuilding the economy. (AP Photo/Susan Walsh)

(AP) ? Seeking to build momentum for looming fiscal fights, President Barack Obama on Wednesday cast himself as the champion for middle-class Americans struggling to make ends meet. He chided Washington for having "taken its eye off the ball" and declared that the economy would be the "highest priority" of his second term.

Obama, in an hour-long address that was at times deeply partisan, also accused Republican lawmakers of succumbing to "an endless parade of distractions and political posturing and phony scandals." He said gridlock had only gotten worse since his re-election.

"I am here to say this needs to stop," Obama said in a speech at Knox College. "This moment does not require short-term thinking. It does not require having the same old stale debates."

Obama, as he often does when criticizing Washington, glossed over his own status as the inhabitant of the city's most powerful office.

GOP leaders quickly panned the president's remarks as a series of repackaged ideas and empty promises.

"It's a hollow shell, it's an Easter egg with no candy in it," House Speaker John Boehner, R-Ohio, said.

Indeed, the president's remarks were void of new policy proposals or fresh solutions for breaking Washington stalemates. And there were no new approaches presented for resolving potential showdowns with Republicans this fall over raising the nation's borrowing limit and curtailing across-the-board federal budget cuts known as "the sequester."

For the president's advisers, a central goal of the speech was simply to refocus Obama's agenda squarely on the economy ahead of the fall deadlines. The first six months of his second term largely have been consumed by priorities like gun control and immigration, as well as an array of foreign policy crises and domestic controversies, including the National Security Agency's domestic spying programs and IRS scrutiny of political groups.

While official Washington's attention was elsewhere, the economy was slowly but steadily improving. The housing market is recovering, the stock market is soaring, and unemployment, while still high at 7.6 percent, is falling.

But the White House fears that standoffs this fall over the debt ceiling and the sequester could upend that progress. The president has declared that he will not negotiate over the debt ceiling and expects Republicans to lift the borrowing limit without concessions. He's also pushing to end the federal budget cuts before they extend into the next fiscal year, which begins Oct. 1.

The president panned the sequester as a "meat cleaver" that has "cost jobs, hurt our military and gutted investments in American education."

Obama will seek to keep up his renewed economic focus in the coming weeks with a series of speeches on manufacturing, education, housing, retirement security and health care. Advisers say some of those speeches will contain more specific policy proposals, both for congressional legislation and executive action.

The president said he welcomed ideas from lawmakers of both parties, but wouldn't stand for reflexive opposition to his own initiatives.

"I'm laying out my ideas to give the middle class a better shot," he said. "Now it's time for you to lay out your ideas."

For Obama, the day trip to Knox College marked a return to the site of his first major economic address. He spoke at the school's graduation ceremony in 2005 as a newly elected U.S. senator.

His remarks back then were strikingly similar to the themes he outlined Wednesday in Illinois and later in Missouri, including the government's role in ensuring all Americans have opportunities to get ahead and the need for the U.S. to be better prepared to compete internationally. Barring action now, Obama said, "We will be waving the white flag while other countries forge ahead in the global economy."

The economy in the surrounding Galesburg community reflects much of the underlying economic concerns facing many Americans. A Maytag plant in the town shut its doors in 2004, leaving hundreds of people unemployed. Today, the factory still sits vacant. Galesburg's unemployment rate is just under 8 percent, and nearly a quarter of its population lives in poverty.

"Those old days aren't coming back," Obama conceded. He said the proposals he will outline in speeches later this summer will be aimed at adapting the U.S. economy to an increasingly competitive and interconnected world.

On education, the president promised "an aggressive strategy to shake up the system, tackle rising costs, and improve value for middle-class students and their families."

During the second stop Wednesday, Obama highlighted a program at the University of Central Missouri in Warrensburg that gives students education and skills at a faster pace while lowering the costs. Students earn a bachelor's degree in two years.

"You are a laboratory for this innovation. ... I want the entire country to notice it," Obama said. "I've asked my team to shake the trees all across the country for some of the best ideas out there for keeping college costs down."

The president also said he would use the speeches he'll give in the coming weeks to renew his calls for increasing the minimum wage and giving all 4-year-olds access to pre-school programs. The first of those speeches will come Tuesday, when Obama visits an Amazon distribution center in Chattanooga, Tenn.

Obama also pledged to take steps to encourage home ownership, make it easier for people to save for retirement and to continue to put in place the elements of his health care law in the face of efforts by Republicans in Congress to repeal, delay or eliminate funding for its various parts.

___

Pace reported from Washington.

___

Follow Darlene Superville on Twitter at http://www.twitter.com/dsupervilleap and Julie Pace at http://twitter.com/jpaceDC

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-07-24-US-Obama/id-d97b6be8a8b545ca9e90940cbc9b10bd

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Wednesday, July 24, 2013

Sarepta stock falls over doubts of faster approval for lead drug

By Zeba Siddiqui

(Reuters) - Sarepta Therapeutics Inc said data from ongoing studies of its lead drug could be enough for the company to apply for a U.S. approval, but that the regulator was unsure if it was enough to fast-track the review process, sparking a sell-off in the company's shares.

The drug, eteplirsen, has been closely watched by the biotechnology community after trial data released in October showed it dramatically improved walking ability in patients suffering from Duchenne muscular dystrophy (DMD) - a rare, degenerative disorder that mostly affects boys and hampers muscle movement.

The drug works by increasing the production of a protein called dystrophin, the lack of which is the chief cause of DMD.

Sarepta on Wednesday said the U.S. Food and Drug Administration did not commit to accepting that production of dystrophin could be considered proof enough of eteplirsen's effectiveness. Some analysts pointed to this ambiguity as the main reason for the share fall.

"We believe the burning question that the Street has been looking for an answer to has not yet been answered," Cowen analysts said in a note.

The agency also asked for more information on the drug's clinical studies and Sarepta said it believes it will be able to respond to the requests and apply for approval in the first half of 2014.

Eteplirsen's efficacy as seen in clinical studies and the absence of other treatments for DMD led to expectations that the FDA could speed up the drug's approval process, by possibly allowing the company to skip conducting a larger, late-stage trial.

Chief Executive Chris Garabedian, on a conference call with analysts, said it is too early to speculate how the FDA may consider the company's marketing application and what type of approval they might consider.

Sarepta shares, which have tripled in value since the October data, fell as much as 17 percent on Wednesday. They had risen 18 percent in premarket trading ahead of the call.

They were trading down 14 percent at $39.62 by midday.

MISREAD BY MARKET?

Eteplirsen's effect has so far only been seen in 12 DMD-affected patients, causing some analysts to question the market's optimism on the drug. Deutsche Bank analysts, for instance, have been critical of eteplirsen for this reason.

The brokerage downgraded Sarepta shares to "hold" from "buy", citing skepticism that eteplirsen would see faster approval, as it believes a competing drug from Dutch company Prosensa Holdings could reach the market earlier.

Prosensa is developing its drug, drisapersen, in partnership with British drugmaker GlaxoSmithKline Plc.

In contrast, Baird analyst Brian Skorney said the likelihood of an FDA approval for eteplirsen in 2014 was stronger following Wednesday's news.

"I think it's a bad misread on the market's part on what Sarepta was saying and what the FDA (is indicating)," Skorney said.

He said the FDA maintained a cautious tone regarding eteplirsen due to the size of the study, but that the agency appeared to have implicitly acknowledged that eteplirsen showed a benefit in treating DMD.

"This is a very preliminary 'hey, is there enough information here to help us make a decision on this next year?'"

(Reporting by Esha Dey and Zeba Siddiqui in Bangalore; Editing by Sreejiraj Eluvangal and Sriraj Kalluvila)

Source: http://news.yahoo.com/sarepta-file-u-approval-drug-first-half-2014-113737807.html

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Obama to try to focus public attention on economy

FILE - In this Aug. 17, 2011 file photo, President Barack Obama reacts to catching a football tossed to him as he visits the Galesburg High School football team in Galesburg, Ill., during a three-day economic bus tour. The president has developed a lasting tie to this small, economically bruised town with an empty refrigerator plant and a liberal arts college where he likes to roll-out big economy speeches. He is scheduled to give an economic speech at Knox College in Galesburg on Wednesday, July 24, 2013. (AP Photo/Carolyn Kaster, File)

FILE - In this Aug. 17, 2011 file photo, President Barack Obama reacts to catching a football tossed to him as he visits the Galesburg High School football team in Galesburg, Ill., during a three-day economic bus tour. The president has developed a lasting tie to this small, economically bruised town with an empty refrigerator plant and a liberal arts college where he likes to roll-out big economy speeches. He is scheduled to give an economic speech at Knox College in Galesburg on Wednesday, July 24, 2013. (AP Photo/Carolyn Kaster, File)

FILE - In this Aug. 17, 2011 file photo, President Barack Obama huddles with the Galesburg High School football team in Galesburg, Ill., during a three-day economic bus tour. The president has developed a lasting tie to this small, economically bruised town with an empty refrigerator plant and a liberal arts college where he likes to roll-out big economy speeches. He is scheduled to give an economic speech at Knox College in Galesburg on Wednesday, July 24, 2013. (AP Photo/Carolyn Kaster, File)

(AP) ? Seeking to focus public attention on the problem he was sent to the White House to solve, President Barack Obama is making a renewed push for policies to expand the middle class, helping people he says are still treading water years after the financial meltdown.

Obama will use a series of back-to-back speeches over two days to take another stab at selling the public on his vision of a thriving economy.

The first of those speeches comes Wednesday when Obama visits the Midwest to speak at Knox College in Galesburg, Ill., where he gave his first major speech as a freshman U.S. senator in 2005 during booming economic times. He is not expected to announce any new initiatives. The president also speaks later in the day at the University of Central Missouri in Warrensburg. The third speech is set for Thursday at the Jacksonville Port Authority in Florida.

The White House is billing Obama's latest speech at Knox College as a major one, comparable in tone to the commencement address he delivered there eight years ago, also about the economy. Back then he talked about how the country can give every American a "fighting chance" in a 21st century transformed by technology and globalization.

The trio of speeches comes as Congress prepares to leave Washington next week for its monthlong August recess. These and other speeches planned for the coming weeks and months are designed to increase public pressure on lawmakers in hopes of avoiding showdowns over taxes and spending in the fall.

The White House believes such stalemates will stunt the economy, which has added more than 200,000 jobs a month in the past six months. The new federal budget year begins Oct. 1 and the government will soon hit its borrowing limit.

Even before Obama spoke, Republican congressional leaders were panning the president's renewed economic focus.

"Every time he goes out and gives one of these speeches, it generates little more than a collective bipartisan eye roll," said Sen. Mitch McConnell, R-Ky. "It's just such a colossal waste of time and energy ? resources that would be better spent actually working with both parties in Congress to grow the economy and create jobs."

House Speaker John Boehner, R-Ohio, said, "Welcome to the conversation, Mr. President. We've never left it."

In his 2005 speech at Knox College, Obama spoke about how technology and globalization and the weakening of labor unions had upended the idea that those who worked hard would be able to get good jobs that paid enough to support their families, provided adequate health care, allowed them to retire with dignity and gave them hope that their children would have a better future.

He was expected to argue Wednesday that those underlying trends haven't been reversed.

"They are still a central challenge that we face," Obama told supporters Monday night in Washington. "There's no more important question for this country than how do we create an economy in which everybody who works hard feels like they can get ahead and feel some measure of security."

Other issues, like stemming climate change, advancing women's and civil rights, and reducing gun violence, are important too, Obama said. "But what we also know is, is that so many of the issues that we care about are more likely to progress if people feel good about their own lives and their economic situation."

Obama said Wednesday's speeches begin a monthslong effort to refocus on the economy. New policy proposals are expected to be included in a series of single-issue, follow-up speeches planned through September.

The economy largely has been overshadowed in the first six months of Obama's second term, partly driven by a White House that chose to invest time and political capital on other parts of his agenda, such as the failed effort to enact stricter gun laws and the push for an immigration bill.

Circumstances outside of the White House's control also played a role, including the civil war in Syria, the coup in Egypt and renewed attention by Congress to the deadly attack on Americans in Libya. Closer to home, the targeting of political groups by the Internal Revenue Service and the seizure of journalists' telephone records by the Justice Department also required large investments of White House time.

The economy has showed slow improvement throughout, registering gains in the housing and stock markets and consumer confidence. The national unemployment rate, though it remains high by historical levels, actually is down to 7.6 percent.

But the coming fiscal deadlines threaten to undo that progress, adding a sense of urgency to the push in Washington and with the public at large to focus on the economy.

___

Follow Darlene Superville on Twitter: http://www.twitter.com/dsupervilleap

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-07-24-Obama/id-ad0e1635d18b4aeeba6216ea9286b238

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Cybercrime estimated to cost U.S. government, businesses $100 billion a year

Cybercrime Annual Cost $100 Billion

That pesky 12-year-old Russian kid who infected your PC with malware that replaced all your photos with gifs of dancing bears is costing the American economy a lot more than you imagine. The Wall Street Journal reports that a new study conducted by McAfee and the nonprofit Center for Strategic and International Studies shows that?cybercrime is costing the U.S. government and businesses around $100 billion per year, or roughly one-tenth of what other recent estimates have projected. The Journal says that ?one of the key reasons the study?s estimate is lower than many previous ones is that it takes into account the shifting benefits of cybertheft,? since data that is stolen by hackers doesn?t actually disappear.

[More from BGR: The smartphone price crash is about to wreck two major vendors]

This article was originally published on BGR.com

Source: http://news.yahoo.com/cybercrime-estimated-cost-u-government-businesses-100-billion-024531686.html

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